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Head of Research Group : Dr. sc.hum. Deni Hardiansyah

The specialization was established as an undergraduate program in Physics in 1998, in collaboration with the Indonesian Nuclear Energy Agency. It was subsequently introduced at the master’s level in 2002. 

Since its establishment, we have been committed to equipping students with in-depth knowledge and strong analytical skills, enabling them to pursue successful careers in scientific research and clinical practice in Medical Physics or Biophysics.

Research and academic activities within this division focus on the application of physics to improve human well-being and are broadly categorized into two areas: Medical Physics and Biophysics.

Medical Physics

According to the International Organization for Medical Physics (IOMP), Medical Physics is a branch of applied physics that applies the principles, methods, and techniques of physics in medical practice and research to prevent, diagnose, and treat human diseases, with the ultimate goal of improving human health and well-being.

Medical Physics encompasses several subfields and specialties, including Radiation Oncology Physics, Medical Imaging Physics, Nuclear Medicine Physics, Medical Health Physics (Radiation Protection in Medicine), Non-ionizing Medical Radiation Physics, and Physiological Measurement. It is also closely related to neighboring disciplines, such as Biophysics, Biological Physics, and Health Physics.

Within our division, research and academic activities focus primarily on three areas: Radiation Oncology Physics, Medical Imaging Physics, and Nuclear Medicine Physics.

Biophysics

The Biophysical Society describes Biophysics as a field that applies the theories and methods of physics to understand how biological systems function. Biophysics plays a crucial role in understanding the molecular mechanisms underlying life, the movement and function of cellular components, and the behavior of complex biological systems, including the brain, circulatory system, and immune system.

Biophysics is a dynamic and interdisciplinary field that brings together researchers from diverse disciplines, including mathematics, chemistry, physics, engineering, pharmacology, and materials science. By integrating knowledge and approaches from these fields, biophysicists develop new tools and methods to investigate and understand the fundamental processes of life.

Within our division, research activities focus primarily on three areas: Biomaterials, Biosensors, and Bioenergy.

Radiotherapy Research Subgroup

Radiation therapy, or radiotherapy, is a major treatment modality for cancer that uses ionizing radiation to destroy cancer cells while minimizing damage to surrounding healthy tissues. The successful delivery of radiotherapy relies on accurate treatment planning, precise dose delivery, and rigorous quality assurance to ensure that the prescribed radiation dose is delivered safely and effectively.

Physics plays a central role in modern radiotherapy, from characterizing radiation beams and calculating dose distributions to verifying treatment plans and evaluating the performance of treatment delivery systems. Advances in medical imaging, computational modeling, and radiation measurement have further enabled the development of highly precise treatment techniques that account for tumor geometry, anatomical changes, and patient motion.

The Radiation Oncology Physics research area within the Medical Physics and Biophysics Research Group at the Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, focuses on developing and evaluating physics-based methods to improve the accuracy, reliability, and safety of radiation therapy. Research activities include radiation dosimetry, treatment planning and dose verification, patient-specific quality assurance, image-guided radiotherapy, and advanced treatment techniques such as small-field radiotherapy and Tomotherapy.

By integrating experimental measurements, computational methods, medical imaging, and quantitative analysis, our research aims to improve treatment accuracy and support the continuous development of safe and effective radiotherapy practices. Through collaboration with clinical and academic partners, we are committed to advancing radiotherapy research, medical physics education, and the application of innovative technologies in cancer treatment.

Diagnostic Radiology Physics Research Subgroup

Diagnostic radiology plays a fundamental role in modern healthcare by providing medical imaging techniques that enable the detection, diagnosis, and monitoring of diseases. Modalities such as X-ray radiography, computed tomography (CT), fluoroscopy, and mammography provide essential information about human anatomy and pathology. The development and effective use of these technologies require a thorough understanding of radiation physics, image formation, detector performance, and radiation safety.

Physics plays a crucial role in optimizing medical imaging by improving image quality while minimizing radiation exposure to patients and healthcare professionals. Through quantitative image analysis, radiation dosimetry, equipment performance evaluation, and quality assurance, medical physicists contribute to the safe, accurate, and efficient use of diagnostic imaging technologies.

The Diagnostic Radiology Physics research area within the Medical Physics and Biophysics Research Group at the Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, focuses on developing and evaluating physics-based methods to improve the quality, safety, and performance of medical imaging systems. Research activities include image quality assessment, radiation dose optimization, quality assurance of diagnostic imaging equipment, and the development of computational tools and imaging phantoms for system evaluation.

Our research also extends to interventional radiology and cardiology, where fluoroscopic imaging is used to guide minimally invasive procedures. By integrating experimental measurements, computational modeling, image analysis, and quantitative evaluation, we aim to develop practical solutions for optimizing imaging protocols, improving diagnostic performance, and promoting radiation protection.

Through interdisciplinary collaboration with medical physicists, clinicians, engineers, and other researchers, we seek to advance diagnostic imaging research, support medical physics education, and contribute to the safe and effective implementation of medical imaging technologies in clinical practice.

Nuclear Medicine Physics Research Subgroup

Nuclear medicine uses radiopharmaceuticals—radioactive compounds administered to patients—to visualize physiological processes and assess organ function for diagnostic purposes, as well as to target diseased tissues for therapeutic applications. By combining molecular imaging with radionuclide-based therapy, nuclear medicine enables the detection and treatment of diseases at the molecular level.

Physics plays a fundamental role in advancing nuclear medicine through quantitative imaging, radiation measurement, dosimetry, and mathematical modeling. These approaches help improve image interpretation, quantify radiopharmaceutical uptake, estimate radiation doses delivered to organs and tumors, and support the development of safer and more personalized treatments.

The Nuclear Medicine Physics research area within the Medical Physics and Biophysics Research Group at the Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, focuses on advancing computational and quantitative methods for nuclear medicine. Research activities include molecular and functional imaging, internal dosimetry, pharmacokinetic modeling, and radiopharmaceutical therapy, particularly molecular radiotherapy and targeted radionuclide therapy.

Our research aims to bridge physics, computational modeling, and biomedical applications to improve the accuracy of radiation dose estimation and support individualized treatment strategies. Through national and international collaborations, we seek to contribute to the advancement of nuclear medicine research, education, and clinical practice.

Biophysics Research Subgroup

Biophysics is an interdisciplinary field that applies the principles, methods, and tools of physics to investigate biological systems, from molecular interactions and cellular processes to complex physiological phenomena. By combining physical principles with experimental measurements, mathematical modeling, and computational approaches, biophysics provides quantitative insights into the mechanisms underlying biological function and human health.

The Biophysics Research Group within the Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, focuses on developing and applying physics-based methods to investigate biological systems, analyze biomedical data, and advance biomedical research. Our research integrates vibrational spectroscopy, biomedical imaging, computational modeling, signal processing, and artificial intelligence to extract meaningful and quantitative information from complex biological measurements.

Our research activities include Raman and Fourier-transform infrared (FTIR) spectroscopy for biochemical characterization and disease-related analysis; biomedical imaging using ultrasound, magnetic resonance imaging (MRI), and photoacoustic techniques; and the application of chemometrics, machine learning, and deep learning to biomedical data analysis. We also explore mathematical modeling and computational simulations to investigate biological processes and develop quantitative approaches for biomedical applications.

By integrating experimental physics with data-driven and physics-based computational methods, our group aims to improve the understanding of biological systems, identify meaningful biochemical and imaging biomarkers, and develop innovative approaches for biomedical characterization and disease assessment. We emphasize reproducible research, interpretable computational methods, and the integration of physical principles with modern data science.

Through interdisciplinary collaboration with researchers in physics, biomedical engineering, medicine, and related fields, we strive to advance biophysical research and contribute to the development of quantitative, non-invasive, and computational approaches for biomedical science and healthcare.