The Herbal Drug Development Research Cluster (HERMED-FKUI) is dedicated to generating high-quality academic outputs, including reputable international scientific publications, monographs, and intellectual property protection for evidence-based herbal innovations.
Dr. Desak Gede Budi Krisnamurti, S.Farm., apt., M.Biomed.
Herbal Drug Development & Molecular Pharmacology
Selected Publications:
- The Effect of Topical and Oral Combination of Ethanolic Extract of Graptophyllum pictum Leaf on Rectoanal Tissue Inflammation in Hemorrhoid-Induced Rats
- Liposome-Based Delivery of Genetic Materials for Anti-Aging Therapy: A Focused Review of microRNA-Oriented Translational Strategies
- Vitamin D Alleviates Obesity in Insulin Resistance Rat Model via Adipokine-Gut Microbiome Regulation
- The Effect of Simvastatin–Acalypha indica Linn. Combination on the Improvement of Fatty Pancreas in Rats Induced with a High Fructose and Cholesterol Diet
Dr. dr. Adisti Dwijayanti, M.Biomed.
Pharmacology, Regenerative Medicine & Anti-Aging
Selected Publications:
- Human Wharton’s Jelly Mesenchymal Stem Cells Improve Insulin Levels and Reduce Weight Gain in Aging Female Rats
- Anti-Oxidative Potential of Acalypha indica L. Root Extract on Brain-Derived Neurotrophic Factor Levels in Old Sprague-Dawley Rats
- Optimization of Loading Methods of Letrozole-Loaded Exosomes: Impact of Passive Drug Loading on Drug Delivery Systems
- Follicular Development of Aged Rats Ovarian Injected Human Umbilical Cord Mesenchymal Stem Cells
Dr. Rani Wardani Hakim, S.Si., apt., M.Biomed.
Pharmacological Properties & Metabolic Research
Selected Publications:
- Centella asiatica Extract Improves Senescence-Associated Metabolic Dysfunction by Targeting Inflammation in Adipose Tissue and Macrophages in Obesity-Induced Insulin Resistance Mice
- Kratom (Mitragyna speciosa) in Cancer Chemoprevention – A Provocative Functional Food Perspective
- Ficus deltoidea Ethanol Extract Cytotoxic Activity on MCF-7 Treated Doxorubicin: An In Silico and In Vitro Approach
- Exploring the Anti-Breast Cancer Potential of Chalcomoracin, Guangsangon E, and Morushalunin: A Computational Analysis of Compounds from Morus sp.
apt. Wilzar Fachri, S.Farm., M.Si.
Drug Delivery Systems & Natural Therapeutics
Selected Publications:
- Simultaneous HPLC Analysis of Asiaticoside and α-Mangostin in Herbal Formulations
- Liposome-Based Delivery of Genetic Materials for Anti-Aging Therapy: A Focused Review of microRNA-Oriented Translational Strategies
- Exploring the Anti-Breast Cancer Potential of Chalcomoracin, Guangsangon E, and Morushalunin: A Computational Analysis of Compounds from Morus sp.
- In Silico, In Vitro and In Vivo Tests of Ficus deltoidea Jack Leaves Extract as Inhibitor for Beta-Catenin Expression in Colon Carcinogenesis Model
Prof. Erni Hernawati Purwaningsih
Natural Product Pharmacology & Phytotherapy
Selected Publications:
- Restoration of Brain Insulin Signaling by Tinospora crispa Extract via PI3K/AKT Pathway Modulation in HFHF-Fed Rats
- Tinospora crispa Attenuates Cognitive Dysfunction and Amyloid–Tau Pathology in a High-Fat High-Fructose-Induced Alzheimer’s Rat Model
- Exploring Hibiscus sabdariffa Linn. Phytochemicals as Potential GLUT1 Regulators: In Silico and HT29 Cell Line Approaches
- 6-Gingerol, a Bioactive Compound of Zingiber officinale, Ameliorates High-Fat High-Fructose Diet-Induced Non-Alcoholic Related Fatty Liver Disease in Rats
Dr. dr. Siti Farida, M.Kes, Ph.D.
Medical Pharmacy & Phytopharmaca Formulations
Selected Publications:
- Treatment of Fatty Pancreas: Acalypha indica Linn. Extract as An Alternative to Simvastatin
- The Administration of Centella asiatica Ethanol Extract Increases AMPA-GluR1 Expression in CA1 Region Hippocampus of Male Wistar Rats
- Subacute Oral Toxicity Test of Chitosan-Alginate Coated Microparticles of Garcinia mangostana Linn Extract
- Antifungal Activity of Microcapsule Propolis from Tetragonula spp. to Candida albicans
Monographs & Scientific Books
In addition to journal publications, members of the HERMED FKUI research team actively co-author academic monographs and books, including works on rational prescription writing and organic medicinal plant cultivation.