Publication

Publication

Publications & Research Works

The Herbal Drug Development Research Cluster (HERMED-FKUI) is dedicated to generating high-quality academic outputs, including reputable international scientific publications, monographs, and intellectual property protection for evidence-based herbal innovations.

Dr. Desak Gede Budi Krisnamurti, S.Farm., apt., M.Biomed.

Herbal Drug Development & Molecular Pharmacology

Selected Publications:

  • The Effect of Topical and Oral Combination of Ethanolic Extract of Graptophyllum pictum Leaf on Rectoanal Tissue Inflammation in Hemorrhoid-Induced Rats
  • Liposome-Based Delivery of Genetic Materials for Anti-Aging Therapy: A Focused Review of microRNA-Oriented Translational Strategies
  • Vitamin D Alleviates Obesity in Insulin Resistance Rat Model via Adipokine-Gut Microbiome Regulation
  • The Effect of Simvastatin–Acalypha indica Linn. Combination on the Improvement of Fatty Pancreas in Rats Induced with a High Fructose and Cholesterol Diet

Dr. dr. Adisti Dwijayanti, M.Biomed.

Pharmacology, Regenerative Medicine & Anti-Aging

Selected Publications:

  • Human Wharton’s Jelly Mesenchymal Stem Cells Improve Insulin Levels and Reduce Weight Gain in Aging Female Rats
  • Anti-Oxidative Potential of Acalypha indica L. Root Extract on Brain-Derived Neurotrophic Factor Levels in Old Sprague-Dawley Rats
  • Optimization of Loading Methods of Letrozole-Loaded Exosomes: Impact of Passive Drug Loading on Drug Delivery Systems
  • Follicular Development of Aged Rats Ovarian Injected Human Umbilical Cord Mesenchymal Stem Cells

Dr. Rani Wardani Hakim, S.Si., apt., M.Biomed.

Pharmacological Properties & Metabolic Research

Selected Publications:

  • Centella asiatica Extract Improves Senescence-Associated Metabolic Dysfunction by Targeting Inflammation in Adipose Tissue and Macrophages in Obesity-Induced Insulin Resistance Mice
  • Kratom (Mitragyna speciosa) in Cancer Chemoprevention – A Provocative Functional Food Perspective
  • Ficus deltoidea Ethanol Extract Cytotoxic Activity on MCF-7 Treated Doxorubicin: An In Silico and In Vitro Approach
  • Exploring the Anti-Breast Cancer Potential of Chalcomoracin, Guangsangon E, and Morushalunin: A Computational Analysis of Compounds from Morus sp.

apt. Wilzar Fachri, S.Farm., M.Si.

Drug Delivery Systems & Natural Therapeutics

Selected Publications:

  • Simultaneous HPLC Analysis of Asiaticoside and α-Mangostin in Herbal Formulations
  • Liposome-Based Delivery of Genetic Materials for Anti-Aging Therapy: A Focused Review of microRNA-Oriented Translational Strategies
  • Exploring the Anti-Breast Cancer Potential of Chalcomoracin, Guangsangon E, and Morushalunin: A Computational Analysis of Compounds from Morus sp.
  • In Silico, In Vitro and In Vivo Tests of Ficus deltoidea Jack Leaves Extract as Inhibitor for Beta-Catenin Expression in Colon Carcinogenesis Model

Prof. Erni Hernawati Purwaningsih

Natural Product Pharmacology & Phytotherapy

Selected Publications:

  • Restoration of Brain Insulin Signaling by Tinospora crispa Extract via PI3K/AKT Pathway Modulation in HFHF-Fed Rats
  • Tinospora crispa Attenuates Cognitive Dysfunction and Amyloid–Tau Pathology in a High-Fat High-Fructose-Induced Alzheimer’s Rat Model
  • Exploring Hibiscus sabdariffa Linn. Phytochemicals as Potential GLUT1 Regulators: In Silico and HT29 Cell Line Approaches
  • 6-Gingerol, a Bioactive Compound of Zingiber officinale, Ameliorates High-Fat High-Fructose Diet-Induced Non-Alcoholic Related Fatty Liver Disease in Rats

Dr. dr. Siti Farida, M.Kes, Ph.D.

Medical Pharmacy & Phytopharmaca Formulations

Selected Publications:

  • Treatment of Fatty Pancreas: Acalypha indica Linn. Extract as An Alternative to Simvastatin
  • The Administration of Centella asiatica Ethanol Extract Increases AMPA-GluR1 Expression in CA1 Region Hippocampus of Male Wistar Rats
  • Subacute Oral Toxicity Test of Chitosan-Alginate Coated Microparticles of Garcinia mangostana Linn Extract
  • Antifungal Activity of Microcapsule Propolis from Tetragonula spp. to Candida albicans

Monographs & Scientific Books

In addition to journal publications, members of the HERMED FKUI research team actively co-author academic monographs and books, including works on rational prescription writing and organic medicinal plant cultivation.