Publication

Our Research Focus

STELLAR (Stem cEll rEsoURces for Advanced-biomedicine Research) focuses on advancing stem cell science through an integrated, multidisciplinary research framework that spans basic discovery, translational research, and advanced biomedical engineering.

STELLAR’s research activities are organized into four interconnected research pillars: iPSCs Clinical Translational Research, Indonesian Immortalized Cell Lines, Organ-on-a-Chip technology, and AI-inspired stem cell technology and nanoengineering. Together, these pillars support the development of robust cellular resources, physiologically relevant disease models, and innovative translational platforms addressing unmet clinical needs.

By integrating in vitro stem cell–based models, advanced histological and molecular analyses, bioengineering approaches, and preclinical evaluation, STELLAR aims to bridge fundamental scientific discovery with translational and clinically relevant applications. Through this coordinated research ecosystem, STELLAR strengthens Indonesia’s capacity in advanced biomedicine and regenerative research while fostering global competitiveness.

Selected Research Projects
  1. The Comparison of Differentiation of Umbilical Cord Mesenchymal Stem Cells into Cardiomyocytes on 2D and 3D Culture (2023–2024)
  2. Mechanism of Preconditioned Extracellular Vesicles–Umbilical Cord Mesenchymal Stem Cells or Combination with Hepatocyte Growth Factor on Rat Liver Biliary Duct Ligation Model (2022–2023)
  3. Direct Programming of Hepatocytes from Preputial Skin Stem Cells: A Genome-Based Liver Regeneration Approach (2018–2020)
  4. iPSC-Based Liver Organoids (2021–2022)
  5. SHiNTA: Stem Cell Hepatic Intuitive Apparatus (2022–2024)
  6. Transplantation of iPSC-Based Liver Organoids (2022–2023)
  7. Isolation and Characterization of Fibroblasts from Normal and Thalassemia Foreskin (2023)
  1. Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Improve Ligament–Bone Integration after ACL Primary Repair in Rabbits (2025)
  2. Isolation and Characterization of Fibroblasts from Normal and Thalassemia Foreskin (2024)
  3. The Use of Cell-Penetrating Peptides for Delivery of Recombinant Transcription Factor DNA into Primary Human Fibroblasts (2023)
  4. Hepatocyte Differentiation from iPSCs or MSCs in Decellularized Liver Scaffold: Cell–ECM Adhesion, Spatial Distribution, and Hepatocyte Maturation Profile (2022)
  5. Liver Organoids Cocultured on Decellularized Native Liver Scaffolds as a Bridging Therapy Improve Survival from Liver Failure in Rabbits (2023)
  6. Induced Pluripotent Stem Cell–Based Liver Organoids: Benefits and Challenges (2023)
  7. Potensi Terapi Sel Punca untuk Sirosis Hati (2018)
Selected Publications