The Infection, Immunology, and Hematology Research Group’s 10-year roadmap progresses through four phases: building the foundation (Years 1–2) with national mapping, registries, biobanks, and capacity building; developing clinical and translational research (Years 3–5) on vaccination responses, biomarkers, and immune dysregulation with multicenter collaboration; translating research into innovation and policy (Years 6–8) through clinical trials, precision medicine, predictive models, and evidence-based guidelines; and establishing a regional Center of Excellence (Years 9–10) by leading international consortia, applying big data and AI, and advancing personalized pediatric immunization strategies.